Influência da Disbiose na Patologia do Couro Cabeludo

Francisca Morgado, R. Oliveira Soares
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Abstract

In recent years, several studies have demonstrated the involvement of the intestinal microbiota in immune-mediated diseases such as diabetes, ulcerative colitis, and multiple sclerosis. There are few data on the follicular microbiome and its role in the pathogenesis of scalp diseases. Some studies show influence of dysbiosis on these diseases, and manipulation of the microbiome may represent a possible therapeu- tic option. This article reviews current knowledge regarding the impact of dysbiosis on dermatological diseases of the scalp, such as seborrheic dermatitis, psoriasis, alopecia areata, androgenetic alopecia, lichen planus pilaris, frontal fibrosing alopecia and decalvant folliculitis. A broader understanding of this may suggest additional treatments beyond conventional therapies.
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生态失调对头皮病理的影响
近年来,一些研究已经证明肠道微生物群参与免疫介导的疾病,如糖尿病、溃疡性结肠炎和多发性硬化症。关于毛囊微生物组及其在头皮疾病发病机制中的作用的资料很少。一些研究显示了生态失调对这些疾病的影响,而控制微生物群可能是一种可能的治疗选择。本文综述了目前关于生态失调对头皮皮肤病的影响的知识,如脂溢性皮炎、牛皮癣、斑秃、雄激素源性脱发、毛癣、额前部纤维化性脱发和脱脂性毛囊炎。对这一点的更广泛的理解可能会建议在常规疗法之外进行额外的治疗。
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