Gender aspect of comorbidities in COPD patients in primary care

K. Klester, E. Klester, V. Elykomov, A. Zharikov, Galina Ermachkova, M. Nikolaeva, E. Mukhtarova
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Abstract

Introduction: a problem of multi-morbidity - the increase in the multiplicity of diseases with age, which reflects, first of all, involutional processes and comorbidity - the deterministic possibility of their combination, is particularly difficult. Objective: to study gender characteristics of comorbid conditions and determine the degree of their influence on mortality in COPD. Materials and Methods: conducted a 6-year clinical observations in COPD p-s (n = 518; 389 were males, mean age - 66,2 ±13,9 years). The Carlson Comorbidity Index (CCI; 1987), the geriatric Cumulative Illness Rating Scale (CIRS-G), Barthel Index (BI) were evaluated. Results: CCI was in group A - 3,2 ± 1,1; in B - 3,8 ± 0,9; in C - 4,6 ± 1,0; in D - 3,9 ± 0,8 (all p 4 scores (odds ratio [OR] 4.92; 95% confidence interval [CI], 3.89-6.34; p Conclusion: Associated pathology forms a syndrome of mutual aggravation, which leads to an increased risk of death in the assessment by CCI with mandatory consideration of gender differences, which should be taken into account in the development of treatment plans for COPD patients.
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初级保健中COPD患者合并症的性别方面
导言:多重发病的问题——随着年龄增长,疾病的多样性增加,这首先反映了发病过程和合并症——它们结合的确定性可能性——特别困难。目的:研究COPD合并症的性别特征,确定其对死亡率的影响程度。材料与方法:对COPD p-s患者进行了为期6年的临床观察(n = 518;男性389例,平均年龄- 66,2±13.9岁)。卡尔森合并症指数;1987)、老年累积疾病评定量表(CIRS-G)、Barthel指数(BI)进行评估。结果:A组CCI为- 3,2±1,1;B - 3,8±0,9;C - 4,6±1,0;D - 3,9±0,8(均为4分)(优势比[OR] 4.92;95%置信区间[CI], 3.89-6.34;p结论:相关病理形成一种相互加重的综合征,导致CCI评估中死亡风险增加,并强制考虑性别差异,在制定COPD患者治疗方案时应考虑到这一点。
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