Placement of endovascular stent-grafts for emergency treatment of acute disease of the descending thoracic aorta.

B. Czermak, P. Waldenberger, R. Perkmann, M. Rieger, I. Steingruber, A. Mallouhi, G. Fraedrich, W. Jaschke
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引用次数: 93

Abstract

OBJECTIVE The aim of this study was to evaluate the feasibility, safety, and effectiveness of endovascular stent-graft placement for the emergency treatment of acute descending thoracic aortic disease. MATERIALS AND METHODS From January 1996 through November 2001, 18 patients underwent emergency endovascular stent-graft placement for various types of acute descending thoracic aortic disease. Five patients had Stanford type B aortic dissection, six had traumatic ruptures of the thoracic aorta, five had ruptured aortic aneurysms, and two had penetrating atherosclerotic aortic ulcers. All patients presented with life-threatening symptoms requiring treatment with stent-grafts from the emergency kit. All were at high surgical risk due to serious comorbidities. The efficacy of the procedure was assessed at follow-up studies before discharge and at 3, 6, and 12 months after intervention and yearly thereafter. RESULTS The primary technical success rate was 78%. Four patients had primary perigraft leaks. The secondary technical success rate was 83%. One patient died 20 hr after intervention from stent-graft-related causes. Follow-up studies revealed stent-graft migration in one patient. Progression of disease was observed in one patient treated for dissection and in both patients treated for penetrating ulcers. One patient died 7 months after intervention of unknown reasons; all other patients are alive. The mean follow-up time was 17.4 months (range, 0-38 months). CONCLUSION Emergency repair of acute descending thoracic aortic disease with stent-graft placement can be successfully accomplished and may be a promising alternative to open-chest surgery, especially in patients at high risk.
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急诊治疗急性胸降主动脉疾病的血管内支架植入术
目的评价血管内支架置入术急诊治疗急性胸降主动脉疾病的可行性、安全性和有效性。材料与方法:从1996年1月到2001年11月,18例急性胸降主动脉疾病患者接受了急诊血管内支架置入术。5名患者患有斯坦福B型主动脉夹层,6名患有创伤性胸主动脉破裂,5名患有破裂的主动脉瘤,2名患有穿透性动脉粥样硬化性主动脉溃疡。所有患者都出现了危及生命的症状,需要使用急救箱中的支架移植进行治疗。由于严重的合并症,所有患者手术风险都很高。在出院前、干预后3个月、6个月和12个月以及此后每年的随访研究中评估该方法的有效性。结果初级技术成功率为78%。4例患者有原发性移植物周围渗漏。二次技术成功率为83%。1例患者在介入治疗20小时后死于支架相关原因。随访研究发现一例患者发生支架移植物迁移。在一名因夹层治疗的患者和两名因穿透性溃疡治疗的患者中观察到疾病进展。1例患者在干预后7个月死亡,原因不明;所有其他病人都还活着。平均随访时间17.4个月(0 ~ 38个月)。结论急诊修复急性降主动脉病变支架置入术可以成功完成,可能是一种有希望的替代开胸手术,特别是对高危患者。
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