TH-7B pneumatically driven sac-type ventricular assist device and drive system.

S Nitta, T Yambe, Y Katahira, T Sonobe, S Naganuma, H Akiho, S Chiba, Y Kakinuma, H Matsuzawa, H Hayashi
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Abstract

TH-7B pneumatically driven sac-type ventricular assist device and drive system including automatic control system were developed and evaluated in the chronic animal experiments. The blood-contacting surfaces of the blood pump are coated with either Cardiothane or Cardiomat. In the chronic experiments using adult goats, only one of fifteen goats showed sudden thrombus formation after 34 pumping days. No gross findings of thrombus formation were observed in any of the cases, except for a thin circular thrombus at the junction of the connectors and the sac of the blood pump. These results suggest that antithrombogenicity of this system was satisfactory for clinical use.

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TH-7B气动囊式心室辅助装置及驱动系统。
研制了TH-7B型气动囊型心室辅助装置及包括自动控制系统在内的驱动系统,并进行了慢性动物实验。血泵的血液接触表面涂有Cardiothane或Cardiomat。在用成年山羊进行的慢性实验中,15只山羊中只有1只在泵血34天后出现突发性血栓形成。除了在连接件和血泵囊的连接处有一个薄的圆形血栓外,在任何病例中都没有观察到血栓形成的明显发现。这些结果表明,该系统的抗血栓性是令人满意的临床应用。
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