Renewed Interest in Cholera Control

S. Bhattacharya
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Abstract

Cholera is an ancient disease of significant public health importance accounting for approximately 1.3-4 million cases worldwide and about 21000–143,000 deaths. Cholera is endemic in many developing countries where sanitation is poor and lack in safe water. The disease has the potential to cause large-scale epidemics and pandemics. The ongoing seventh pandemic has spread to more than 100 countries since its origin in 1961 in Indonesia. Travellers from developed countries travelling to cholera endemic areas are at higher risk of getting cholera. Oral rehydration therapy (ORT) has revolutionized the treatment of cholera and causes reduction of mortality. ORT has saved the lives of millions of children all over the world and is considered the single most significant discovery in medicine of the century. Effective oral cholera vaccines have been developed and are being used but not to its full potential to control cholera. Since the disease burden due to cholera is huge and we have the tools to combat cholera, particularly reduce mortality, it is imperative that the global communities should embark on cholera control as an urgent priority of human health. Cholera control should be viewed as a poverty alleviation programme for the marginalised population. The current pandemic of COVID-19 overwhelmed the economy and healthcare systems so much so that the health authorities undermined the cholera control measures even during ongoing epidemics of cholera. The World Health Organization (WHO) has reframed the strategy with renewed interest on cholera control with a target of reducing the mortality from cholera by 90 percent by 2030. Member countries should mobilize enough funds for the programme and actively implement it. Improvement of sanitation and safe water for all should continue as long-term solution for combating the menace of cholera.
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重新关注霍乱控制
霍乱是一种具有重大公共卫生重要性的古老疾病,全世界约有130万至400万病例,约有2.1万至14.3万人死亡。霍乱在卫生条件差和缺乏安全饮用水的许多发展中国家流行。该病有可能引起大规模流行和流行病。目前正在进行的第七次大流行自1961年起源于印度尼西亚以来已蔓延到100多个国家。从发达国家前往霍乱流行地区的旅行者感染霍乱的风险较高。口服补液疗法(ORT)彻底改变了霍乱的治疗方法,降低了死亡率。ORT挽救了全世界数百万儿童的生命,被认为是本世纪医学上最重要的发现。有效的口服霍乱疫苗已经开发出来并正在使用,但尚未充分发挥其控制霍乱的潜力。由于霍乱造成的疾病负担巨大,而且我们拥有防治霍乱的工具,特别是降低死亡率,因此全球社会必须着手控制霍乱,将其作为人类健康的紧急优先事项。霍乱控制应被视为一项针对边缘人口的扶贫方案。当前的COVID-19大流行给经济和卫生保健系统带来了巨大压力,以至于卫生当局甚至在持续的霍乱流行期间破坏了霍乱控制措施。世界卫生组织(世卫组织)重新制定了战略,重新关注霍乱控制,目标是到2030年将霍乱死亡率降低90%。各成员国应为该方案筹集足够资金并积极实施。改善卫生设施和为所有人提供安全饮用水应继续作为防治霍乱威胁的长期解决办法。
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