Coagulopathy and Hyperinflammation in COVID-19

Abstract

August 2020 • HEMATOLOGY 25 COVID-19, a disease resulting from SARS-CoV-2 infection, generally results in mild-to-moderate illnesses in those affected. However, 15% of symptomatic patients develop severe interstitial pneumonia, with 5% going on to develop profound and life-threatening complications including acute respiratory distress syndrome, sepsis, hyperinflammatory syndromes, and multiorgan failure. Clinical complications of COVID-19 include myocarditis, acute myocardial infarction, heart failure, venous thromboembolism, and cerebrovascular events. These vascular and thromboembolic complications suggest a coagulopathic impairment requiring specialist haematological examination and input. THROMBOSIS