Rapid development of multiple squamous-cell carcinomas during chronic granulocytic leukemia.

Dermatologica Pub Date : 1991-01-01 DOI:10.1159/000247631
P Disdier, J R Harle, J J Grob, C Weiller-Merli, G Magalon, P J Weiller
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引用次数: 23

Abstract

We report a 65-year-old patient who presented a rapid eruption of keratoses on sun-exposed areas and an explosive transformation into several squamous-cell carcinomas, occurring during the accelerated phase of a chronic granulocytic leukemia. Clinical findings resembled those usually described in xeroderma pigmentosum. The role of immunosuppression, chemotherapy and possible genetic predisposition is discussed.

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慢性粒细胞白血病多发鳞状细胞癌的快速发展。
我们报告一位65岁的患者,在慢性粒细胞白血病的加速期,出现了暴露在阳光下的角化病的快速爆发,并爆炸性地转变为几个鳞状细胞癌。临床表现与色素性干皮病相似。讨论了免疫抑制、化疗和可能的遗传易感性的作用。
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[RETICULOSARCOMA]. [Infectious diseases]. Linear pemphigus vulgaris along a surgical scar. Eccrine porocarcinoma. Elevated glucocorticoid receptor concentrations before and after glucocorticoid therapy in peripheral mononuclear leukocytes of patients with atopic dermatitis.
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