Release of nerve growth factor from cultured aortic smooth-muscle cells.

Blood vessels Pub Date : 1991-01-01 DOI:10.1159/000158899
T Ueyama, M Hamada, T Hano, I Nishio, Y Masuyama, A Ooshima
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引用次数: 11

Abstract

Conditioned medium from cultured aortic smooth-muscle cells from rat aorta yielded neurite-extending effects on sensory and sympathetic ganglia of chick embryos. These effects were blocked by adding specific antiserum against 2.5S nerve growth factor (NGF), suggesting that NGF might be released from vascular smooth-muscle cells.

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培养的主动脉平滑肌细胞释放神经生长因子。
用培养的大鼠主动脉平滑肌细胞条件培养基对鸡胚感觉神经节和交感神经节有神经突延伸作用。添加2.5S神经生长因子(NGF)特异性抗血清可阻断上述作用,提示NGF可能从血管平滑肌细胞释放。
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