Plants screening and laboratory investigation of Ageratina adenophora methanol extract against Anopheles stephensi

Abstract

Laboratory investigation of Ageratinaadenophora methanol leaf extract fractions (A. adenophora-MLEFr) was controlled and using GC-MS analysis, highlights of the main components on malarial vector, Anopheles stephensi(An. stephensi). In phytochemical, characterized by GC-MS analysis was carried out to be eligible for the constituents of the MLE. Maximum mortality was exerted by Fr-1 was showed EH/ENH% ovicidal activity of 15.7/37.2% at 10 ppm and 100% mortality at 20, 30, 40 50 and 60 ppm, against An. stephensi. The repellent activity of Fr-1 was the highest, showing 100% protection up to 240 min at 0.75 mg/cm2. In GC-MS analyzes, a total of 21 compounds were identified in the A. adenophora-MLE, and the main component was 5-isopropyl-2-methylphenol. The reports revealed the 5-isopropyl-2-methylphenol was the main constituent provides malarial control for the vector mosquito from A. adenophora-MLEFr