{"title":"A Realistic Model of VOR Motor Learning with Spiking Cerebellar Cortical Neuronal Network","authors":"Keiichiro Inagaki, Yutaka Hirata","doi":"10.1109/ISPACS.2006.364790","DOIUrl":null,"url":null,"abstract":"The vestibuloocular reflex (VOR) stabilizes our vision during head movements. The VOR is under adaptive control which requires the cerebellar flocculus, especially its highly organized neuronal network with various synaptic plasticities. To elucidate the signal processing in cerebellar flocculus during VOR adaptation, we constructed a mathematical model in which the cerebellar cortical neuronal network is explicitly described by integrate-and-fire neurons based upon the known anatomy and physiology. Model simulations confirmed that the model reproduces characteristic Purkinje cell simple spike discharge patterns and eye movements during VOR, optokinetic response, and various visual-vestibular mismatch paradigms in normal and flocculectomized monkeys","PeriodicalId":178644,"journal":{"name":"2006 International Symposium on Intelligent Signal Processing and Communications","volume":"56 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2006-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2006 International Symposium on Intelligent Signal Processing and Communications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ISPACS.2006.364790","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
The vestibuloocular reflex (VOR) stabilizes our vision during head movements. The VOR is under adaptive control which requires the cerebellar flocculus, especially its highly organized neuronal network with various synaptic plasticities. To elucidate the signal processing in cerebellar flocculus during VOR adaptation, we constructed a mathematical model in which the cerebellar cortical neuronal network is explicitly described by integrate-and-fire neurons based upon the known anatomy and physiology. Model simulations confirmed that the model reproduces characteristic Purkinje cell simple spike discharge patterns and eye movements during VOR, optokinetic response, and various visual-vestibular mismatch paradigms in normal and flocculectomized monkeys