Statistical analysis for COVID-19 infections including several association factors: Age, gender and blood parameters

Abstract

Clinical manifestations of COVID-19 caused by the new coronavirus SARS-CoV-2 are associated with several blood parameters. In this report we investigate the relation between COVID-19 susceptibility to the gender, ABO blood, patient's age and blood parameters. Blood samples of 50 patients were analysed for five months to detect ferritin, D-dimer, CR Protein, W. BCs count, COVID-19 IgM and COVID-19 IgG. According to the gender of the cases. The results showed that number of male's incidence is higher than in females (31case-62% male) (19 case-38%) respectively. The incidence of COVID-19 in.age period 30-42 years showed the highest number for both genders. The ABO blood group investigations showed that cases with blood group A+ were the highest percentage and the lowest was in the AB+ blood group for both genders. The blood parameters were significant elevated;ferritin (95% Confidence Interval CI: 304.7-540.2, Median 198.3, Range (IQR) 1163.11), the reactive protein (CRP) titre significant elevated (95% CI, 62.11-93.73 mg/L, median of CRP titre 59) and D-Dimer (95% CI, 0.5647-1.039mg/L, median of D-Dimer titre 0.4 while Range (IQR) 3. Higher levels of white blood cell (95% CI, 10.55-12, median of WBC 10.94). Finally, elevated titre of IgG, CI 95% 2. 926-4.966, Median 2.405, Range (IQR) 17.03. Whereas, IgM CI 95% 6.905-12.04 Median 6.14, Range (IQR) 44.53). In summary, our results showed that COVID-19 impact significantly on ferritin, D-dimer, CR Protein, W. BCs count, IgM and IgG. Additionally, there was a significant association between COVID-19 predisposition and the ABO blood group. Persons with blood group A have a higher risk comparing with blood group AB individuals, how have a lower risk for COVID-19 infection. Based on the results of the study, it demonstrated a correlation between older age and change in blood parameters post Covid-19 infection. Current study suggest that aged people and blood group A might need particularly more awareness to protect and reduce the possibility of infection. © 2022 Author(s).