[Studies about the therapy of tuberculosis in East Germany (former GDR)].

R Schnorr, E U Hafa, S Merkel, I Schalldach
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Abstract

On the basis of a questionnaire the therapy of 2285 patients with tuberculosis was evaluated for the years 1987-1989. The data of the GDR National Tuberculosis Register (9827 patients) were used for statistical comparison. 85% of the patients had a pulmonary tuberculosis, 947 patients (41% of all) excreted tubercle bacilli in the sputum. The average duration of treatment was 31.8 weeks, 94.7% of the patients were hospitalised for treatment for an average time of 12.4 weeks, the following outpatient treatment was 19.4 weeks in average. The initial phase (daily-treatment) in all cases of tuberculosis was 8.6 weeks, the follow-up phase was 23.2 weeks (all data are averages). The intermittent outpatient drug administration was made in 95% of cases under nurse control in outpatient departments. The initial treatment was started in 92.1% with 3 or 4 drugs (H/R/Z/S or E). Isoniacid and rifampicin were prescribed in 89.7% and pyrazinamide was used as a 4th drug. In the follow-up phase the combination isoniacid and rifampicin was employed intermittent in 75.7%. The delaytime for the evaluated cases was 38.8 days in average. The result of study shows, in most cases the patients were treated according to the recommendation of therapy. The clinical stay of patients is too long.

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[关于东德(前民主德国)结核病治疗的研究]。
在问卷调查的基础上,对1987-1989年2285例肺结核患者的治疗进行了评价。采用德意志民主共和国国家结核病登记簿(9827例)数据进行统计比较。85%的患者有肺结核,947例(41%)患者痰中有结核菌。平均治疗时间为31.8周,94.7%的患者住院治疗时间平均为12.4周,后续门诊治疗时间平均为19.4周。所有结核病病例的初始阶段(每日治疗)为8.6周,随访期为23.2周(所有数据均为平均值)。门诊在护士控制下,95%的病例进行了门诊间歇给药。采用3、4种药物(H/R/Z/S或E)进行初始治疗的占92.1%,异烟酸加利福平的占89.7%,吡嗪酰胺为第4种药物。在随访阶段,有75.7%的患者间歇使用异烟酸和利福平联合用药。评估病例的延迟时间平均为38.8天。研究结果表明,大多数患者都是按照推荐的治疗方法进行治疗的。病人的临床停留时间过长。
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