Arsenic safe water and changes in severity of arsenical symptoms

K. Majumdar, M. Goyal
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Abstract

Limited information is available in the literature regarding the long-term effect of chronic arsenic toxicity after stoppage of consumption of arsenic-containing water. Treatment options for the management symptoms of chronic arsenicosis are also limited. Mitigation option available for dealing with the health problem of ground water arsenic contamination rests mainly on supply of arsenic safe water in arsenic endemic region of Indo-Bangladesh subcontinent. The current study was therefore done to study the prevalence of arsenicosis and to assess the effect of drinking arsenic safe water (<50µg/L) on disease manifestation of arsenicosis. Manifestations of various skin lesions and systemic diseases associated with chronic arsenic exposure was ascertained initially by carrying on baseline study on 191 families having 1097 family members along with 44 children studying in Chouduar Primary School in Chouduar village of Malda District of West Bengal. The study population was taking water solely from a particular Chouduar primary school tube well with arsenic level >50 µg/L. The base line study findings were compared objectively at the end of six months follow up period after installation of a community filter at the Chouduar primary school tube well. Around 11.36% of school children had clinical features of suspected arsenicosis with mild keratosis either in the palm or sole. The prevalence was more common in males. 15.8% of the remaining study population was having one or more dermatological and non dermatological manifestations of arsenicosis and there was 1.94% decrease in prevalence of non dermatological manifestations without any change in dermatological manifestations after taking arsenic safe water at the end of 6 months of follow up study. Around 70% of population was not aware about adverse health effects of arsenicosis and not taking animal protein regularly.
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砷安全水与砷中毒症状严重程度的变化
关于停止饮用含砷水后慢性砷中毒的长期影响,文献资料有限。慢性砷中毒的管理症状的治疗选择也有限。可用于处理地下水砷污染健康问题的缓解办法主要取决于在印度-孟加拉国次大陆砷流行区域供应砷安全水。因此,目前的研究是为了研究砷中毒的患病率,并评估饮用砷安全水(50 µg/L)的效果。在Chouduar小学管井安装社区过滤器后的六个月随访期结束时,对基线研究结果进行客观比较。约11.36%的学龄儿童有疑似砷中毒的临床特征,并伴有手掌或足底轻度角化病。患病率在男性中更为常见。15.8%的剩余研究人群有一种或多种皮肤和非皮肤表现的砷中毒,在6个月的随访研究结束时,服用砷安全水后,非皮肤表现的患病率下降了1.94%,皮肤表现没有任何变化。约70%的人口没有意识到砷中毒对健康的不良影响,也没有定期摄入动物蛋白。
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