Design And Simulate MEMS Based Cantilever Biosensor For Detection of Tuberculosis

Abstract

In the medical field various disease detection methods are under developmental stage. Due to this most of the diseases are not prevent in time and death rate are increases. By increasing the death rate those diseases are come in top ten diseases in the world. One of the hardly detectable disease is Tuberculosis. Every year millions of people were suffering from this disease, due to its complicated structure, recognition of it is very tedious job. Most of the traditional methods take long time to diagnose due to which patient not get proper treatment in time and it may cause of death. Now a day for disease detection biosensor plays an important role. In this paper Cantilever biosensor is designed and simulated for rapid detection of tuberculosis. The surface of cantilever is coated with antibodies and it gets binds with antigen. When the targeted molecules are finds, the surface get stress and it form deflection. Five different models with various materials are designed and discover the maximum displacement. The maximum displacement achieved 1.71 x 1028 µm from model-3 with gold layer on the cantilever for a 100N load corresponds to 28.228 x 10-24 kg weight of antigen.