Revival of Landing's Concept of Infantile Obstructive Cholangiopathy – A Plea to Hand Over the 2 Week Old Jaundiced Full Term Neonate to the Surgeon!

Shilpa Sharma, D. Gupta
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Abstract

The concept of infantile obstructive cholangiopathy started in 1974 by Landing and remained till early 1980s. However, the concept has not been used much since then as nothing new has developed over the last 40 years sufficient enough to change the course of the disease or identify its etiology. This review article is an attempt to consolidate evidence on review of literature pointing towards a common etiopathological process leading to the spectrum of anomalies constituting neonatal cholestasis. The importance of early referral of any case with neonatal jaundice in a full term neonate, preferably at 2 weeks age is highlighted. This will help to identify and treat more cases within the correctable range and prevent the disease from progressing to a life threatening situation especially in developing countries where the resources for liver transplantation are meagre. DOI: http://dx.doi.org/10.3329/jpsb.v1i1.19465
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婴儿梗阻性胆管病概念的复兴——呼吁将2周大黄疸足月新生儿交给外科医生!
婴儿梗阻性胆管病的概念始于1974年,一直持续到20世纪80年代初。然而,从那时起,这个概念就没有被广泛使用,因为在过去的40年里,没有任何新的发展足以改变疾病的进程或确定其病因。这篇综述文章是试图巩固文献综述的证据指向一个共同的病因病理过程导致频谱异常构成新生儿胆汁淤积症。早期转诊的重要性与新生儿黄疸的任何情况下,足月新生儿,最好是在2周龄被强调。这将有助于识别和治疗更多的病例在矫正范围内,防止疾病发展到危及生命的情况下尤其在发展中国家的资源为肝移植是微薄的。DOI: http://dx.doi.org/10.3329/jpsb.v1i1.19465
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