C Weikel, A Lazenby, P Belitsos, M McDewitt, H E Fleming, M Barbacci
{"title":"Intestinal injury associated with spiramycin therapy of Cryptosporidium infection in AIDS.","authors":"C Weikel, A Lazenby, P Belitsos, M McDewitt, H E Fleming, M Barbacci","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Two of three patients treated with high doses of spiramycin for Cryptosporidium infection developed acute intestinal injury. Spiramycin at high doses may be directly toxic to the intestinal epithelium and thus may have limited utility as therapy for cryptosporidiosis in AIDS patients.</p>","PeriodicalId":22758,"journal":{"name":"The Journal of protozoology","volume":"38 6","pages":"147S"},"PeriodicalIF":0.0000,"publicationDate":"1991-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of protozoology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Two of three patients treated with high doses of spiramycin for Cryptosporidium infection developed acute intestinal injury. Spiramycin at high doses may be directly toxic to the intestinal epithelium and thus may have limited utility as therapy for cryptosporidiosis in AIDS patients.
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