[Characterization of immunological responses to bone and cartilage xenografts].

H Schmidt, S Völkel
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Abstract

The immunological responses to subcutaneous bone and cartilage grafts were investigated in rats using phenol oxidase, a leukocyte labelling enzyme. The resulting development of granulomas reflects a cell-mediated immunological process and is proof of the immunogenicity of bone and cartilage. This method is a new criterium for the assessment of the biocompatibility of graft and implant materials.

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异种骨和软骨移植的免疫反应特征。
利用白细胞标记酶苯酚氧化酶研究了大鼠对皮下骨和软骨移植的免疫反应。由此产生的肉芽肿反映了细胞介导的免疫过程,证明了骨和软骨的免疫原性。该方法为移植体和植入体材料的生物相容性评价提供了新的标准。
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