ウルソデオキシコール酸(UDCA)治療で肝機能異常の改善を認めた肝サルコイドーシスの1例

文子 齋藤, 真史 高野, 俊治 海瀬, 康文 内海, 直彦 郡司, 良一 石幡, 篤志 入澤, 弘正 大平
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引用次数: 3

Abstract

: A 38-year-old man was admitted to our hospital with a diagnosis of pulmonary sarcoidosis accompanied with elevated biliary enzyme levels. Various imaging modalities, and percutaneous liver biopsy confirmed the diagnosis of hepatic sarcoidosis. Abnormalities of biliary enzymes improved after the administration of ursodeoxycholic acid (UDCA). In this case, the mechanism of pharmacologic action was considered to be the glucocorticoid-like effect of UDCA. UDCA might be a therapeutic option for hepatic sarcoidosis without general symptoms.
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一例通过乙羟胆酸(UDCA)治疗,肝功能异常得到改善的肝结节中毒
一名38岁男性因肺结节病伴胆酶水平升高而入院。多种影像学检查和经皮肝活检证实了肝结节病的诊断。胆酶异常在熊去氧胆酸(UDCA)治疗后得到改善。在这种情况下,药理学作用机制被认为是UDCA的糖皮质激素样作用。UDCA可能是无一般症状的肝结节病的治疗选择。
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