Nanobiotechnology for the Detection and Control of Waterborne Parasites

W. Hikal, Amra Bratovcic, Rowida S Baeshen, K. Tkachenko, H. Ahl
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引用次数: 8

Abstract

Nowadays, the fast development of nanobiotechnology, has led to rapid diagnosis of important infectious diseases such as arboviruses-borne diseases, vector-borne infections and waterborne parasites diseases and others in order to reduce and avoid further dissemination of the infections within the general population. Furthermore, new nanomedicines based on the application of silver and gold nanoparticles which are less toxic, more effective, and that does not generate resistance could help to solve the problems of parasitic disease like leishmaniasis and chagas disease. It turns out that the combination of nanoparticles with antibiotics not only reduces the toxicity of both agents towards human cells but also enhances their ability to destroy bacteria by facilitating the binding of antibiotics to the microbes. Moreover, combining nanoparticles with antimicrobial peptides and essential oils with nanoparticles generates genuine synergy against microbial resistance.
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纳米生物技术在水媒寄生虫检测与控制中的应用
如今,纳米生物技术的快速发展,已经导致了重要传染病的快速诊断,如虫媒病毒传播的疾病、媒介传播的感染和水传播的寄生虫病等,以减少和避免感染在普通人群中的进一步传播。此外,基于银和金纳米粒子应用的新型纳米药物毒性更小、更有效,而且不会产生耐药性,可能有助于解决利什曼病和恰加斯病等寄生虫病的问题。事实证明,纳米颗粒与抗生素的结合不仅降低了这两种药物对人体细胞的毒性,而且通过促进抗生素与微生物的结合,增强了它们摧毁细菌的能力。此外,将纳米颗粒与抗菌肽和精油与纳米颗粒结合可以产生真正的协同作用,对抗微生物耐药性。
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