{"title":"Effects of buthobendin and epinephrine on glycolytic energy formation and magnesium concentration in vitro and in vivo.","authors":"M Gumińska, T Kedryna, E Marchut, M Stachurska","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Buthobendin activated glycolytic lactate formation stronger than epinephrine and increased the ATP level, both in vitro in rabbit myocardial slices and in vivo in rabbit blood. These effects were accompanied by an increase in extracellular magnesium concentration, which was probably related to the inhibitory effect of buthobendin on the membrane-bound ATPases.</p>","PeriodicalId":20276,"journal":{"name":"Polish journal of pharmacology and pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1991-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polish journal of pharmacology and pharmacy","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Buthobendin activated glycolytic lactate formation stronger than epinephrine and increased the ATP level, both in vitro in rabbit myocardial slices and in vivo in rabbit blood. These effects were accompanied by an increase in extracellular magnesium concentration, which was probably related to the inhibitory effect of buthobendin on the membrane-bound ATPases.
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