[Differentiation of cells of the bronchial wall in the early period of embryonal development of the lungs].

A L Zashikhin
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Abstract

Electron microscopical analysis of cellular elements of the developing lung has been performed during early stages of the prenatal development. The mesenchymal anlage of the organ is characterized with an essential cell polymorphism. The precursors of the smooth myocytes are formed on the 13th day of embryogenesis and they develop in a close contact with epithelial tubules. Synthesis and accumulation of contractile elements are determining signs of myoblasts differentiation. Already at first stages of differentiation they interact by means of specialized junctions of adhesive type and from clusters, situating on periphery of the epithelial tubules. Increase in amount of contractile filaments in cytoplasm of myoblasts is accompanied with formation of the basement membrane of these cells. Together with myoblasts in the mesenchyme, cells of fibroblastic differon at various levels of development are described.

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[肺胚胎发育早期支气管壁细胞的分化]。
在产前发育的早期阶段进行了肺细胞元素的电子显微镜分析。器官的间充质分析以基本的细胞多态性为特征。平滑肌细胞的前体在胚胎发生的第13天形成,它们与上皮小管密切接触。收缩因子的合成和积累是决定成肌细胞分化的标志。在分化的第一阶段,它们通过粘附型的特化连接和位于上皮小管周围的簇来相互作用。成肌细胞的细胞质中收缩丝的数量增加,并伴有基底膜的形成。与间充质中的成肌细胞一起,描述了不同发育水平的成纤维细胞。
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