Systemic circulation with high frequency blood flow--analysis from neurophysiological point of view.

T Yambe, S Nitta, Y Katahira, T Sonobe, S Naganuma, Y Kakinuma, H Akiho, M Tanaka, T Fukuju, M Miura
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Abstract

The vibrating electromagnetically driven univalved artificial heart, which provided more than 10 1/min at 10 Hz/sec. vibration, was developed in our team. This vibrating electromagnetic pump (VEMP) produced the original flow pattern compared with the flow pattern of the natural heart, so that circulatory regulatory system during maintain the circulation with VEMP must be investigated before the clinical application. In order to assess the effect of high frequency blood flow produced by the VEMP from the neurophysiological point of view, power spectral analysis of the hemodynamics was performed. VEMP was implanted as the total left heart bypass in adult goats and right heart circulation was maintained by natural hearts. In arterial blood pressure during maintain circulation by the high frequency blood flow, Mayer waves (0.01-0.15 Hz) were significantly decreased, though respiratory waves (0.25-0.40 Hz) were not significantly changed. These results suggest that circulatory regulatory system was influenced by the high frequency blood flow produced by the VEMP.

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高频血流的体循环——从神经生理学的角度分析。
电磁驱动的振动式单阀人工心脏,以10hz /sec的速度提供100.1 /min以上的电流。《振动》是我们团队开发的。这种振动电磁泵(VEMP)产生的血流模式与天然心脏的血流模式相比较,因此在临床应用前必须对VEMP维持循环过程中的循环调节系统进行研究。为了从神经生理学的角度评估VEMP产生的高频血流的影响,对血流动力学进行功率谱分析。将VEMP植入成年山羊左心全搭桥,由天然心脏维持右心循环。高频血流维持循环时动脉血压,梅耶波(0.01 ~ 0.15 Hz)明显降低,呼吸波(0.25 ~ 0.40 Hz)无明显变化。这些结果表明,VEMP产生的高频血流影响了循环调节系统。
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