[Metaphyseal and diaphyseal fractures of the femur resulting in growth inequality in children under 3 years of age].

V Guzzanti, A Di Lazzaro, F Falciglia
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Abstract

The authors clinically and radiographically review 42 of 53 children between the ages of 5 months and 3 years treated by closed means from 1983 to 1987 for femoral fracture (average follow-up, 4 years). Evaluation of a large number of patients in this particular age group offers several advantages: a) it regards a phase of evolution in which the modalities of growth do not affect in any significant way the metabolic balance of the growth plate chondrocyte, as occurs in periods of rapid growth. This makes the sample group statistically homogeneous; b) it eliminates the age variable in the search for the factors which may contribute to limb-length discrepancy. The importance of the following factors was statistically analyzed: location, type, and initial displacement of the fracture, accuracy of reduction, and characteristics of the traumatic event. There was a significant correlation between a large degree of limb lengthening and further reduction or corrective procedures under general anesthesia. Overlapping reduction and limb shortening were also closely related. A highly significant correlation was also found between limb lengthening exceeding 15 mm. (range, 15-22 mm.) and the time of day at which the trauma occurred (9-10 pm). The results of treatment suggest the need for a reevaluation, using recently gained knowledge, of Lacroix's theory of the pathogenesis of this disorder as well as the need to examine more thoroughly, with further clinical and experimental studies, the hormonal changes following the trauma.

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[3岁以下儿童股骨干骺端和干骺端骨折导致生长不均匀]。
作者回顾了1983年至1987年53例5个月至3岁儿童中42例(平均随访4年)的临床和影像学资料。对这一特定年龄组的大量患者的评估提供了几个优势:a)它考虑了一个进化阶段,在这个阶段,生长方式不会以任何显著的方式影响生长板软骨细胞的代谢平衡,就像在快速生长时期发生的那样。这使得样本组在统计上是同质的;B)在寻找可能导致四肢长度差异的因素时,它消除了年龄变量。统计分析以下因素的重要性:骨折的位置、类型和初始位移、复位的准确性和创伤事件的特征。在全身麻醉下,肢体延长的程度与进一步复位或矫正手术有显著的相关性。重叠复位与肢体缩短也密切相关。肢体长度超过15毫米(范围15-22毫米)与创伤发生时间(晚上9-10点)之间也存在高度显著的相关性。治疗结果表明,有必要利用最近获得的知识,重新评估拉克鲁瓦关于这种疾病发病机理的理论,并需要通过进一步的临床和实验研究,更彻底地检查创伤后的激素变化。
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