[Changes in systemic pressure during experimental injury of the thoracic spinal cord].

Abstract

The hemodynamic changes in experimental injury of spinal medulla were known as studied under the general anesthesia. Authors performed the thoracic spinal cord impact trauma in rabbits. They stated the character of this "sympathetic shock" is the same as in narcosis. Immediately after the injury, the phase of increase in systemic pressure occurred which lasted for 10 s, then the phase of decrease in pressure followed lasting 10 min. In spite of significant pressure changes (p less than 0.05) which occurred through the experiment, these changes were not so large to override the autoregulatory capacities of cerebrospinal vessels. Our experimental results obtained under the local anesthesia are comparable with those described in literary sources, though obtained from the experimentation under the general anesthesia. It outflows from our results that the pharmacological influence on the spinal lesion may be reliably studied also under the general anesthesia.