[Oncogene expression in malignant head and neck neoplasia].

A Sartoris, P Aluffi, A Montemagno, E V Gerbaudo, M Gariglio, G P Cavallo
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Abstract

Cellular oncogenes may acquire transforming properties and take part in induction or progression of tumors. In the present study we have examined the expression of c-met, c-ras and c-myc in some head and neck carcinomas. In 3 tumors we have found an elevated expression of the c-met oncoprotein, in 2 tumours of the c-myc one. These data suggest that oncogenes could participate in the development of some head and neck cancers.

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[头颈部恶性肿瘤的癌基因表达]。
细胞癌基因可能获得转化特性并参与肿瘤的诱导或进展。在本研究中,我们检测了c-met, c-ras和c-myc在一些头颈癌中的表达。在3个肿瘤中,我们发现c-met癌蛋白的表达升高,在2个c-myc肿瘤中。这些数据表明致癌基因可能参与了一些头颈癌的发展。
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