[The anatomicohistological characteristics of the formation of the mucosa of the human small intestine in the prenatal period of ontogeny].

Abstract

The time, when the first villi appear, is defined. Quantitative composition, percent content, height of the villi of the mucous membrane in all parts of the small intestine during various periods of the intrauterine development are presented. In 17-week-old embryos at the level of the duodenum the first villi are noted and their formation in the middle part of the intestinal tube is revealed. By the 8th-9th weeks of development they appear at the level of the caudal part of the intestine. This demonstrates asynchronism of their formation in the cranio-caudal direction. The periods of their intensive growth in height in the first part of the intestine correspond to 8-10, 12-16, 24 weeks of the fetus age, in the second part--to 8-10, 18-20 weeks, in the third--to 10-12, 16-18, 26-28 weeks. These periods alternate with an abatement in growth intensity, which is connected with an increasing width of the villi themselves, with amount of newly formed villi and with changes of the intestinal tube diameter. The form of the villi is rather variable.