Chronic pancreatitis progressing to duodenal obstruction in the absence of classic symptoms.

Henry Ford Hospital medical journal Pub Date : 1991-01-01
J R Condit, D K Wong
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Abstract

We report the case of a 34-year-old alcoholic who was initially seen in March 1985 because of acute pancreatitis. A mass was demonstrated in the head of the pancreas. Serial sonogram and computed tomography scans over 4 1/2 years revealed progressive encroachment of the duodenum without symptoms attributable to obstruction. In 1989, three separate endoscopies with multiple biopsies showed chronic inflammation and strictures. Hypotonic duodenography confirmed stricture and obstructed duodenum. Surgical intervention is being considered. Duodenal obstruction secondary to chronic pancreatitis is rare. It may proceed subclinically for several years independent of continued alcohol use. Only when obstruction became severe in our patient did the classic symptoms of postprandial nausea, emesis, and weight loss become manifest. Obstructive jaundice from chronic pancreatitis due to stricture in the pancreatic portion of the common bile duct is uncommon.

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在没有典型症状的情况下,慢性胰腺炎进展为十二指肠梗阻。
我们报告一例34岁酗酒者,1985年3月因急性胰腺炎首次就诊。胰腺头部可见肿块。连续4年半的超声和计算机断层扫描显示十二指肠进行性侵犯,无梗阻症状。1989年,三次独立的内窥镜检查和多次活检显示慢性炎症和狭窄。低张力十二指肠造影证实十二指肠狭窄和梗阻。正在考虑手术干预。十二指肠梗阻继发于慢性胰腺炎是罕见的。它可以持续亚临床数年,不依赖于继续饮酒。只有当梗阻变得严重时,我们的病人才出现餐后恶心、呕吐和体重减轻的典型症状。慢性胰腺炎梗阻性黄疸是由胆总管胰部狭窄引起的,并不常见。
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