Generation of Reactive Oxygen Species in Biological Systems

G. Bartosz
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引用次数: 35

Abstract

Reactive oxygen species include oxygen-derived free radicals (superoxide, hydroxyl radical, nitric oxide) and non-radical oxygen derivatives of high reactivity (singlet oxygen, hydrogen peroxide, peroxynitrite, hypochlorite). The main routes of their formation in living organisms include interaction of physical agents with cells and organisms, autoxidation of biochemical intermediates and xenobiotics, and biochemical synthesis for the sake of defense or signaling.
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生物系统中活性氧的产生
活性氧包括氧衍生自由基(超氧化物、羟基自由基、一氧化氮)和高反应性的非自由基氧衍生物(单线态氧、过氧化氢、过氧亚硝酸盐、次氯酸盐)。它们在生物体中形成的主要途径包括物理因子与细胞和生物体的相互作用、生化中间体和外源物的自氧化以及为防御或信号传递而进行的生化合成。
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