{"title":"Optimum Conditions in Preparative Liquid Chromatography. II. Selection of Column Dimensions","authors":"K. Hupe, B. Hoffmann","doi":"10.1080/01496398708057617","DOIUrl":null,"url":null,"abstract":"Abstract The amount of substance that can be separated per unit of time (the production rate) and the purity of the isolated compounds are the determining quantities in preparative chromatography. The production rate in combination with a certain resolution (i.e., a certain selectivity and a certain number of theoretical plates) are therefore the overruling optimization criteria for the design and operation of a preparative chromatographic system.","PeriodicalId":184327,"journal":{"name":"Preparative-Scale Chromatography","volume":"20 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1987-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Preparative-Scale Chromatography","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/01496398708057617","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Abstract The amount of substance that can be separated per unit of time (the production rate) and the purity of the isolated compounds are the determining quantities in preparative chromatography. The production rate in combination with a certain resolution (i.e., a certain selectivity and a certain number of theoretical plates) are therefore the overruling optimization criteria for the design and operation of a preparative chromatographic system.
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