Controversies regarding the natural history and treatment of syphilis in HIV disease.

AIDS clinical review Pub Date : 1991-01-01
E C Tramont
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Abstract

Because of the immunologic dysfunction of HIV-infected patients, concomitant infection with T. pallidum requires that maximal doses of appropriate antibiotics be given, and the expected falls in nontreponemal antibody titer cannot be relied upon to certify a cure. Genital ulcer disease appears to increase the risk of acquiring HIV. Therefore, all HIV-infected persons and persons with syphilis should be tested for both syphilis and HIV.

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关于梅毒在HIV疾病中的自然史和治疗的争议。
由于hiv感染患者的免疫功能紊乱,伴发梅毒螺旋体感染需要给予最大剂量的适当抗生素,而预期的非螺旋体抗体滴度下降不能作为治愈的依据。生殖器溃疡疾病似乎增加了感染艾滋病毒的风险。因此,所有艾滋病毒感染者和梅毒患者都应进行梅毒和艾滋病毒检测。
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Human immunodeficiency virus prevention: applying the lessons learned. Novel strategies toward the development of an effective vaccine to prevent human immunodeficiency virus infection or acquired immunodeficiency virus. Can immune responses to human immunodeficiency virus be preserved, enhanced, or restored? Drug interactions of antiretroviral agents. Salvage therapy for patients failing their current antiretroviral regimen.
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