L-ARGININE SYNTHESIS BY LACTIC ACID BACTERIA

K. Karapetyan, F. Tkhruni, A. Tsaturyan, E. Minasyan, T. Balabekyan
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Abstract

. The results of experimental and clinical studies indicate that L-arginine is a nutritionally essential amino acid for animal health. Additionally, L-arginine or L-citrulline may provide novel and effective therapies for obesity, diabetes, and the metabolic syndrome. The screening of lactic acid bacteria (LAB) strains according to L-arginine synthesis showed significant intra-species differences. The 45 strains of LAB were investigated to L-arginine synthesis capability. It was shown, that some LAB strains (52%) are able to synthesized L-arginine (mg/ml). It was shown, that among 10 strains of L. rhamnosus species, 60% of strains are able to synthesized L-arginine. Two strains Lactobacillus rhamnosus 20–12 and Lactobacillus plantarum 66 shown increasing of L-arginine during growth in both nutrient media (MRS, milk). The L. rhamnosus 20–12 and L.plantarum 66 potential probiotic strains can be used as a basis of functional food product for application in veterinary and medicine.
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乳酸菌合成l -精氨酸
. 实验和临床研究结果表明,l -精氨酸是动物健康所必需的营养氨基酸。此外,l -精氨酸或l -瓜氨酸可能为肥胖、糖尿病和代谢综合征提供新颖有效的治疗方法。根据l -精氨酸合成对乳酸菌(LAB)菌株的筛选显示出明显的种内差异。对45株乳酸菌的l -精氨酸合成能力进行了研究。结果表明,部分LAB菌株(52%)能够合成l -精氨酸(mg/ml)。结果表明,在10株鼠李糖菌中,60%的菌株能够合成l -精氨酸。两株鼠李糖乳杆菌20-12和植物乳杆菌66在两种营养培养基(MRS、牛奶)中均表现出l -精氨酸含量增加的趋势。鼠李糖乳杆菌20-12和植物乳杆菌66具有开发兽药功能食品的潜力。
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