[Reference values for quantitative image analysis of indocyanine green video-fluorescence angiography].

Abstract

Indocyanine green video-fluorescence angiography was performed in 46 healthy normal subjects between the ages of 20 and 81 years using a 30 degrees Zeiss fundus camera, an external light supply and a high resolution CCD camera. Pictures were directly stored in a picture analysis system based on a PC with a temporal resolution of 25 pictures per second. Using statistical picture analysis, choroidal blood-flow parameters were obtained in a round area of interest with a diameter of 8 degrees with the center in the fovea. The parameters include: the mean arterial filling time (AFT) and the mean capillary density (MCD) in the choroid. There was no correlation for one of these parameters with arterial blood pressure or intraocular pressure. All values for the AFT were on an equal level for normal subjects younger than 65 years. Older normal subjects in some cases had clearly increased arterial filling times. The density of the capillary network in the choroid was significantly reduced with increasing age, and there was reduced density of the capillary network in normals with myopia.