[Gemfibrozil in the treatment of hyperlipoproteinemias].

Vutreshni bolesti Pub Date : 1991-01-01
D Monova, V Petrova, N Belovezhdov
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Abstract

30 patients with primary hyperlipoproteinemia (type II and IV according to Fredrickson) were treated with Gemfibrosil (Gevinon--film tablets of 450 mg of "Parke-Davis Company") for a period of 45 days with a daily dose of two tablets taken with the evening meal. The results of the treatment were a decrease of the total cholesterol (with 16.34%), of triglycerides (with 34.50%), of low density lipoproteins (with 10.76%) and of very low density lipoproteins (with 49.21%) and an increase of the high density lipoproteins (with 2.34%). Gevilon was well tolerated. No side effects requiring discontinuing of the treatment were registered.

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[吉非罗齐治疗高脂蛋白血症]。
30例原发性高脂蛋白血症患者(根据Fredrickson的说法是II型和IV型)接受Gemfibrosil (Gevinon- 450 mg“Parke-Davis Company”的薄膜片)治疗,每天服用两片,随晚餐服用,为期45天。治疗的结果是总胆固醇(16.34%)、甘油三酯(34.50%)、低密度脂蛋白(10.76%)和极低密度脂蛋白(49.21%)降低,高密度脂蛋白(2.34%)增加。吉维隆耐受性良好。没有记录到需要停止治疗的副作用。
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