Lung cancer management in low and middle-income countries - current challenges and potential solutions

D. Uprety, Malini Surapaneni
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Abstract

Lung cancer is the second-most prevalent cancer and, the most common cause of cancer-related mortality throughout the world. Evidence-based strategies to decrease its incidence and mortality are being implemented in different parts of the world. Smoking cessation policies are being actively publicized to decrease the incidence of tobacco related cancers including lung cancer. Screening program for early detection of localized lung cancer which can then be targeted by a multimodality approach utilizing surgery, radiation, chemoimmunotherapy to achieve cure is now becoming the standard in several high-income countries. Precision medicine in lung cancer is booming with metastatic non-curative cancers targeted with small molecule tyrosine kinase inhibitors. However, these advancements are not available all around the world. Inequalities exist in the management of lung cancer, mostly driven by the economic differences between the countries. Raising awareness to these international barriers is pivotal for improving lung cancer related incidence and mortality.
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低收入和中等收入国家的肺癌管理——当前的挑战和潜在的解决办法
肺癌是世界上第二常见的癌症,也是导致癌症相关死亡的最常见原因。世界各地正在实施以证据为基础的战略,以减少其发病率和死亡率。正在积极宣传戒烟政策,以减少包括肺癌在内的与烟草有关的癌症的发病率。早期发现局部肺癌的筛查计划,然后通过多模式方法利用手术、放疗、化学免疫治疗来实现治愈,现在已成为几个高收入国家的标准。肺癌的精准医疗正在蓬勃发展,转移性非治愈性癌症以小分子酪氨酸激酶抑制剂为目标。然而,这些进步并不是在世界各地都能得到。在肺癌管理方面存在不平等,主要是由国家之间的经济差异造成的。提高对这些国际障碍的认识对于改善肺癌相关发病率和死亡率至关重要。
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