EPIDEMIOLOGIC EVALUATION OF ACUTE VIRAL BRONCHIOLITIS (AVB) IN INFANTS HOSPITALIZED

Diliene de Moura Flores, A. Bachi, C. Nunes França, T. Konstantyner
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Abstract

OBJECTIVE: To characterize the epidemiological profile of AVB and to identify prognostic factors of clinical complications of infants admitted to a pediatric intensive care unit (PICU). METHODS: Prospective cohort study of 61 infants with a clinical diagnosis of AVB admitted to the PICU from June/2016 to July/2017. All infants were followed up during the hospitalization period for clinical and laboratory data collection. In addition, it was carried out an interview with the mothers or legal guardians to obtain socioeconomic information and morbid antecedents. RESULTS: Mean age was 6.9 months, the length of PICU stay was 8.4 days, the prematurity rate was 27.9%, 62.7% presented anemia, and the presence of household smoking 56.7%. Pneumonia (34.4%) and atelectasis (26.2%) were the most prevalent clinical complications. In addition, pneumonia was associated with hospitalization time longer than seven days (OR=3.91, p=0.020), severe dyspnea on admission (OR=3.75, p=0.020), and thinness (OR=3.54, p=0.040). None associations were observed for atelectasis. CONCLUSION: The epidemiological data presented in this study can be applied to the improvement of actions targeting ABV control actions in infants, not only by the identification of the prognostic factors associated with pneumonia but also especially by the necessity to provide greater attention and care to infants with AVB who are thinness and present severe dyspnea on admission to the PICU.
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住院婴儿急性病毒性细支气管炎(avb)流行病学评价
目的:描述AVB的流行病学特征,并确定儿科重症监护病房(PICU)婴儿临床并发症的预后因素。方法:对2016年6月至2017年7月PICU收治的61例临床诊断为AVB的婴儿进行前瞻性队列研究。在住院期间对所有婴儿进行随访,收集临床和实验室数据。此外,还对母亲或法定监护人进行了访谈,以获取社会经济信息和发病前情。结果:患儿平均年龄6.9个月,PICU住院时间8.4 d,早产率27.9%,贫血62.7%,家庭吸烟56.7%。肺炎(34.4%)和肺不张(26.2%)是最常见的临床并发症。此外,肺炎与住院时间超过7天(OR=3.91, p=0.020)、入院时严重呼吸困难(OR=3.75, p=0.020)和消瘦(OR=3.54, p=0.040)相关。未观察到与肺不张相关。结论:本研究提供的流行病学数据可以应用于改善针对婴幼儿ABV控制行动的措施,不仅可以通过识别与肺炎相关的预后因素,而且特别是需要对入PICU时出现严重呼吸困难的瘦弱AVB婴儿给予更多的关注和护理。
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