Studies of aqueous humor proteins in rabbits after posterior chamber lens implantation.

Lens and eye toxicity research Pub Date : 1991-01-01
Kałuzny, J Rózyczka, A Gutsze, A Mierzejewski, W Pieniazek
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Abstract

In 13 rabbits, 1 month to 1 year after posterior chamber lens implantation/polymethylmetacrylate/, the level of aqueous humor proteins was evaluated and the proteins separation in polyacylamide gel was performed. The studies were also carried out in unoperated eyes of the same animals and control group was composed of the eyes before surgery. It was found that in pseudophakic eyes an increased level of proteins remained during the whole year/the highest one month after surgery, slowly decreasing afterwards/, with the appearance of additional fractions. The moderate increase of the proteins concentration was also observed in unoperated eyes. The increase of aqueous humor proteins in pseudophakic eyes indicates that the presence of polymethyl metacrylate is not completely indifferent to the eyeball in spite of the suggestions derived from the clinical observations.

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兔后房镜植入术后房水蛋白的研究。
采用聚甲基丙烯酸甲酯/后房体植入术后1个月~ 1年13只家兔,测定房水蛋白水平,并进行聚丙烯酰胺凝胶蛋白分离。该研究还在同一动物未手术的眼睛上进行,对照组由手术前的眼睛组成。结果发现,假性晶状眼的蛋白水平在手术后的一个月内保持了一年/最高的水平,之后缓慢下降/出现了额外的部分。未手术眼蛋白浓度也有中度升高。假性晶状眼房水蛋白的增加表明,聚甲基丙烯酸甲酯的存在与眼球并非完全无关,尽管从临床观察得出的建议。
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