Nonleast-squares jackknife regression in drug design.

Drug design and delivery Pub Date : 1991-04-01
P P Mager
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Abstract

Nonleast-squares jackknife regression was applied to model a quantitative structure-activity relationship (QSAR) analysis of butyrophenones. Dependent physicochemical and dependent psychopharmacological parameters were correlated, and the robustness of the model was confirmed by resampling.

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药物设计中的非最小二乘折刀回归。
采用非最小二乘折刀回归对丁苯酮进行了定量构效关系分析。依赖的物理化学参数和依赖的精神药理学参数相互关联,并通过重新采样证实了模型的稳健性。
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