The role of the ketogenic diet in patients with epilepsy. A brief literary review and a clinical example

M. Bobylova, E. I. Novyachkova, K. S. Romanovskaya, L. N. Mukhina, K. Mukhin
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Abstract

Despite the advances in pharmacology, there are still some patients with drug-resistant inoperable epilepsy. Individual ketogenic diet might be an effective measure to prevent seizures. A ketogenic diet must be used only after consulting a dietitian, since it has contraindications and may cause complications. This article focuses on the mechanism of action of the ketogenic diet, indications and contraindications to it, and also describes our experience of using ketogenic diet in a patient with structural focal epilepsy and a typical history of the disease, side effects of antiepileptic drugs, and low compliance of antiepileptic therapy.
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生酮饮食在癫痫患者中的作用。一个简短的文献回顾和一个临床例子
尽管药理学取得了进步,但仍有一些耐药癫痫患者无法手术治疗。个体生酮饮食可能是预防癫痫发作的有效措施。生酮饮食必须在咨询营养师后使用,因为它有禁忌症,并可能引起并发症。本文重点介绍生酮饮食的作用机制、适应证和禁忌症,并介绍我们在一例典型的结构性局灶性癫痫患者中使用生酮饮食的经验、抗癫痫药物的副作用以及抗癫痫治疗的低依从性。
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