M Böck, L Greither, A Gudden, H Diehm, M U Heim, W Mempel
{"title":"[Storage of thrombocyte concentrates: ultrastructural and functional changes].","authors":"M Böck, L Greither, A Gudden, H Diehm, M U Heim, W Mempel","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Optimal storage of platelet concentrates is still an unsolved problem. The present paper demonstrates changes in morphology and function of stored platelets. Transmission microscopy reveals a loss of organelles as well as a progredient destruction of cell membranes during storage. At the same time in vitro aggregability is clearly diminished. Therefore, further investigations seem to be necessary to improve storage conditions of platelets.</p>","PeriodicalId":77545,"journal":{"name":"Infusionstherapie (Basel, Switzerland)","volume":"18 3","pages":"137-8, 141-2"},"PeriodicalIF":0.0000,"publicationDate":"1991-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infusionstherapie (Basel, Switzerland)","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Optimal storage of platelet concentrates is still an unsolved problem. The present paper demonstrates changes in morphology and function of stored platelets. Transmission microscopy reveals a loss of organelles as well as a progredient destruction of cell membranes during storage. At the same time in vitro aggregability is clearly diminished. Therefore, further investigations seem to be necessary to improve storage conditions of platelets.
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