[Acceptance and subjective well-being with a norgestimate combination pill].

Gynakologische Rundschau Pub Date : 1991-01-01
R Schoberberger, P Husslein, M Kunze
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引用次数: 0

Abstract

683 women were assessed in the present study. All study participants were subjected to an overall clinical examination before and after a 4-month regimen of a low-dose norgestimate-containing combination oral contraceptive (Cileste); in addition, their subjective well-being was investigated by an appropriate questionnaire. 63.3% of the study participants rated drug tolerance as 'very good' and 23.0% rated it as 'good' at evaluation in the 4th cycle. Between the first and second evaluation, we observed a significant improvement of the depressive mood and of skin and hair problems. Women with skin and hair problems often suffer from 'severe dysmenorrhea'. This difference was statistically significant only at the first evaluation (i.e. before the combined norgestimate regimen) and was not observed in the 4th cycle (i.e. during the Cileste regimen), while the incidence of menstrual disturbances was generally found to decrease.

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[接受度和主观幸福感与预估组合药丸]。
本研究对683名妇女进行了评估。所有研究参与者在使用低剂量含诺孕酮的复方口服避孕药(Cileste) 4个月前后接受了全面的临床检查;此外,通过适当的问卷调查他们的主观幸福感。在第4周期的评估中,63.3%的研究参与者认为耐受性“非常好”,23.0%的研究参与者认为耐受性“好”。在第一次和第二次评估之间,我们观察到抑郁情绪和皮肤和头发问题的显著改善。有皮肤和头发问题的女性经常遭受“严重痛经”的折磨。这种差异仅在第一次评估(即联合norgestimate方案之前)具有统计学意义,而在第四个周期(即在Cileste方案期间)未观察到,而月经紊乱的发生率普遍下降。
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