Hemodynamic parameters assessment

Abstract

The present work focuses an experimental and theoretical approach to non-invasive cardiovascular (CV) system monitoring. The CV diseases are currently one of the leading causes of death in the developed countries. The development of early diagnostic tools contributes for the early identification of important markers in the CV development. A piezoelectric (PZ) probe to arterial pressure waveform (APW) monitoring at peripheral arteries, such as carotid artery was developed. A dedicated test bench capable of emulating the main CV dynamic properties was developed, providing an interesting tool to carry out the preliminary tests. The PZ probe output signal suffers additional processing to original waveform recovering. The deconvolution method was used for this purpose. Algorithms to waveform delineation were developed, based on the wavelet transform and probability density function (PDF). The AIx was calculated for each one of the developed algorithms. These methods were comparatively evaluated with the reference value from the synthesis procedure. The probe's performance was assessed using realistic simulation based on exponential pulses and in in vivo data acquisitions, Results demonstrate that the developed probe exhibits a good performance with maximum errors less than 0.5% in the AIx determination.