Development of an efficient Computational Model for classification of Tissue remodeling

Zarsha Nazim, Dr.Sajid Mahmood, Kiran Amjad
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Abstract

Tissue remodeling is one of the most important and crucial biological process. Process in which tissue reorganization and renovation takes place is called tissue remodeling. Mean of recovery in human beings is tissue remodeling in which damaged tissue are replaced completely with new tissue or through tissue repairmen types physiological and pathological tissue remodeling are two derivatives of Tissue remodeling. Normal Tissue remodeling is referred to as Physiological tissue remodeling, however abnormal process which may lead to a disease is known as pathological tissue remodeling. From past till now different techniques like histopathology and chemicals were being used to identify abnormality in tissues. Which is a time taking and costly processes. There is no such computational method which can be used for the identification of the physiological and pathological tissue remodeling. The current article aims to develop a classification model which has ability to classify weather the given sequence is physiological or pathological process. Three classifiers RF, ANN and SVM will be used for practice and evaluation of proposed classification model.
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组织重塑分类的高效计算模型的开发
组织重塑是最重要、最关键的生物过程之一。组织重组和更新的过程被称为组织重塑。人体恢复的方式是组织重塑,即损伤组织被新组织完全取代或通过组织修复,生理性和病理性组织重塑是组织重塑的两种衍生形式。正常组织重构被称为生理性组织重构,而可能导致疾病的异常过程被称为病理性组织重构。从过去到现在,组织病理学和化学等不同的技术被用来识别组织中的异常。这是一个耗时且昂贵的过程。目前还没有这样的计算方法可以用于生理和病理组织重塑的识别。本文旨在建立一种能够区分给定序列是生理过程还是病理过程的分类模型。将使用RF、ANN和SVM三种分类器对所提出的分类模型进行实践和评估。
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