Coriocarcinoma testicular con metástasis a coroides

Abstract

Introduction

Testicular tumors make up close to 1% of malignant tumors in men and 6% of the patients present with the disease between the ages of 20 and 35 years. Choriocarcinoma is a highly metastatic malignant tumor derived from undifferentiated trophoblasts. Ocular involvement in testicular tumors is extremely rare and occurs in 0.2% of cases.

Materials and methods

A 23-year-old man's disease symptoms began with intense headache associated with visual disturbances in the left eye and vertigo. He was referred to the Urology Department due to an enlarged left testis with a hardened consistency. Choriocarcinoma of the testis with metastases to the choroid, lung, and central nervous system was reported. After a cycle of chemotherapy, the patient presented with rapid deterioration of his vital functions and died in the intensive care unit. The pathology report stated metastatic testicular choriocarcinoma.

Discussion

Eighteen cases have been reported worldwide and the majority had very poor outcome. Prognosis in these cases was poor until the introduction of cisplatin-based chemotherapy in 1970. Choriocarcinoma is an aggressive variant of testicular carcinoma and has a high metastatic potential. Despite its hematogenous spread, it rarely metastasizes to the choroid.

Conclusions

Choriocarcinoma is an aggressive strain of testicular carcinoma with rapid hematogenous dissemination. Metastasis to the choroid is rare. Despite the combination of radiotherapy and chemotherapy, our patient's state of health deteriorated rapidly.