A Randomized Double Blind Placebo Controlled Study Of Prophylactic Gabapentin For Prevention Of Postoperative Pain And Morphine Consumption In Patients Undergoing Mastectomy.

Aquib Butt, K. Mohammad, Mohamad Ommid, Mubashir Ahmad, N. Jehan, Shigufta Qazi
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引用次数: 6

Abstract

: 50 patients each of ASA I –II were randomly allocated to two study groupsone group received gabapentin (1200mg) and other group received placebo 1 hour prior to surgery. Both groups received morphine (0.1mg/kg) as intraoperative analgesic at induction of anaesthesia. After the completion of mastectomy postoperative analgesia was assessed with visual analogue scale (VAS) method (0cmno pain and 10cmworst possible pain). Rescue analgesic was administered to patients whose VAS was above 3 (morphine 0.1mg/kg).Apart from VAS haemodynamic parameters and oxygen saturation were regularly recorded half hourly for first two hours, then hourly for next 4 hours and then 2 hourly till the patient requested for analgesia postoperatively.
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预防性加巴喷丁用于预防乳房切除术患者术后疼痛和吗啡消耗的随机双盲安慰剂对照研究
:将 50 名 ASA I - II 级患者随机分配到两个研究组,一组在手术前 1 小时服用加巴喷丁(1200 毫克),另一组服用安慰剂。两组患者在麻醉诱导时均接受吗啡(0.1 毫克/千克)作为术中镇痛剂。乳房切除术结束后,采用视觉模拟量表(VAS)法评估术后镇痛效果(0 厘米无痛,10 厘米最痛)。除视觉模拟量表外,还定期记录血流动力学参数和血氧饱和度,头两小时每半小时记录一次,接下来的4小时每小时记录一次,然后每2小时记录一次,直到患者要求术后镇痛为止。
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