A Comparative Study of Neurocognitive Impairment in Elderly Patients with Schizophrenia and Elderly Normals

A. Singh, N. Khan, A. Kanchan, K. S. Sengar, A. Nag
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Abstract

Background: Cognitive impairment has been known to be a feature of Schizophrenia since the illness was first described in a systematic manner. The course of cognition and functional status in schizophrenia remains an area of significant controversy and is marked by conflicting findings. One of the reasons for this controversy is that cognitive and functional changes occur with normal aging in the population. Method: Total number of samples in the study were 80 (experimental and control), out of which 40 were elderly schizophrenic patients and 40 were normal elderly individuals. Elderly patients with schizophrenia were selected from the inpatient department of RINPAS, Ranchi. Normal elderly people were selected from near by areas of the hospital. On both the groups the Post Graduate InstituteBattery for Assessment of Mental Efficiency in Elderly (PGIAMEE) test was administered. Result: Significant differences were found in mental efficiency between normal elderly group and elderly schizophrenic patients. The mean score of normal population is 52.90 and for schizophrenic group 40.20. Conclusion: The findings of the index study suggests that the marked differences in cognitive functioning has been found between elderly patient with schizophrenia and normal elderly people .Areas of impairment were difficulty in recalling names of different things ,general orientation and visuo-spatial coordination.
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老年精神分裂症患者与老年正常人神经认知功能障碍的比较研究
背景:认知障碍被认为是精神分裂症的一个特征,因为这种疾病第一次被系统地描述。精神分裂症的认知过程和功能状态仍然是一个有重大争议的领域,并以相互矛盾的发现为标志。这一争议的原因之一是,认知和功能的变化是随着人口的正常衰老而发生的。方法:本研究共80例(实验组和对照组),其中老年精神分裂症患者40例,正常老年人40例。老年精神分裂症患者选自兰契市RINPAS医院住院部。正常老年人是从医院附近地区挑选的。两组均采用研究生院老年人心理效率评估(PGIAMEE)测试。结果:正常老年人与老年精神分裂症患者在心理效率上存在显著差异。正常人群平均得分为52.90分,精神分裂症组平均得分为40.20分。结论:指数研究结果表明,老年精神分裂症患者的认知功能与正常老年人存在显著差异,障碍领域主要表现在记忆事物名称困难、一般定向障碍和视觉空间协调障碍。
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