Intentional Death Caused by the Overdose of Nonprescription Drugs: An Autopsy Case of Acetaminophen Poisoning

Abstract

Acetaminophen or paracetamol (N-acetyl-paraaminophenol [APAP]) is an effective antipyretic and mild analgesic drug and is widely used as a representative nonprescription medication worldwide. Although there is a general perception that the use of APAP is safe for the public, it can be fatal as either accidental or intentional overdose can cause hepatotoxicity. APAP overdose accounts for 8.8% (276/3,125) of all cases of fatalities due to poisoning in the United States in 2018 [1]. In addition, it is the most common cause of acute liver failure not only in the United States but also in several European countries, including Great Britain [2]. Korean J Leg Med 2020;44:134-139 https://doi.org/10.7580/kjlm.2020.44.3.134