Glucagon and insulin responses to alpha-adrenergic subtype receptor blockade in sheep.

S Oda, A Ohneda, T Tsuda, Y Sasaki
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Abstract

1. Five sheep were used to investigate the influences of alpha-adrenergic subtype receptor blockade on the secretion of both glucagon and insulin. 2. The glucagon secretion was stimulated through an alpha 2-adrenergic subtype mechanism. 3. The secretion of insulin was inhibited by an alpha 2-adrenergic subtype mechanism in conscious sheep.

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胰高血糖素和胰岛素对α -肾上腺素能亚型受体阻断的反应。
1. 采用5只羊,研究α -肾上腺素能亚型受体阻断对胰高血糖素和胰岛素分泌的影响。2. 通过α 2-肾上腺素能亚型机制刺激胰高血糖素分泌。3.清醒羊的胰岛素分泌受α 2-肾上腺素能亚型机制抑制。
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