The development and characterization of clinical intracavity ultrasonic applicators for hyperthermia

C. Diederich, K. Hynynen
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引用次数: 1

Abstract

Cylindrical transducer elements, with sizes and operating frequencies favorable for applications in hyperthermia, are characterized. The effects of cutting these elements from whole cylinders down to halves and quarters (cuts parallel to axis), as well as the resonant frequency of operation (0.5, 1.0, and 1.6 MHz), were investigated. These results were used to develop clinical applicators consisting of multiple elements, one device for each frequency. These clinical applicators were operated with the controlled cooling of the tissue/applicator interface. The efficacy of these applicators were tested in vivo in the canine prostrate, rectal wall, and vaginal wall. The ability of these clinical applicators to provide controlled heating for different tumor geometries is discussed.<>
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用于热疗的腔内超声应用器的发展和特性
圆柱形换能器元件的尺寸和工作频率有利于热疗的应用。研究了将这些元件从整个圆柱体切割成两半和四分之一(切割平行于轴)的效果,以及工作的谐振频率(0.5,1.0和1.6 MHz)。这些结果被用于开发由多个元件组成的临床应用器,每个频率一个装置。这些临床涂敷器在组织/涂敷器界面的控制冷却下操作。在犬的前列腺、直肠壁和阴道壁上测试了这些涂药器的有效性。讨论了这些临床应用器为不同的肿瘤几何形状提供可控加热的能力
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