Carl G. Gahmberg, Pekka Nortamo, Carmela Kantor, Matti Autero, Pekka Kotovuori, Leena Hemiö, Rosalba Salcedo, Manuel Patarroyo
{"title":"The pivotal role of the Leu-CAM and ICAM molecules in human leukocyte adhesion","authors":"Carl G. Gahmberg, Pekka Nortamo, Carmela Kantor, Matti Autero, Pekka Kotovuori, Leena Hemiö, Rosalba Salcedo, Manuel Patarroyo","doi":"10.1016/0922-3371(90)90036-V","DOIUrl":null,"url":null,"abstract":"<div><p>Cellular adhesion is of fundamental importance in leukocyte physiology. It is a complex, strictly regulated process, which involves the participation of several cell surface glycoproteins. Among the most important are the Leu-CAMs or the DC11 / CD18 integrin receptors, and their adhesion ligands ICAM-1 (CD54) and ICAM-2. In this review we summarize some recent work on various aspects of these molecules.</p></div>","PeriodicalId":77508,"journal":{"name":"Cell differentiation and development : the official journal of the International Society of Developmental Biologists","volume":"32 3","pages":"Pages 239-245"},"PeriodicalIF":0.0000,"publicationDate":"1990-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0922-3371(90)90036-V","citationCount":"16","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell differentiation and development : the official journal of the International Society of Developmental Biologists","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/092233719090036V","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 16
Abstract
Cellular adhesion is of fundamental importance in leukocyte physiology. It is a complex, strictly regulated process, which involves the participation of several cell surface glycoproteins. Among the most important are the Leu-CAMs or the DC11 / CD18 integrin receptors, and their adhesion ligands ICAM-1 (CD54) and ICAM-2. In this review we summarize some recent work on various aspects of these molecules.
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