Impact of Electromagnetic Field Generated by Mobile Phone on Prooxidant/Antioxidant Balance in Frontal Brain Cortex of Rats

P. Sowa, Karolina Sieroń, G. Cieślar, A. Sieroń
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Abstract

In this paper the potentially harmful impact of electromagnetic field generated by mobile phone $(\mathbf{f}=\mathbf{900\ MHz})$ on the prooxidant/antioxidant balance in frontal brain cortex of male rats was estimated by means of analysis of the contents of markers of oxidative stress and membrane lipid peroxidation, as well as the activity of selected antioxidant enzymes. It was concluded that 4-week lasting exposure (4 minutes daily) of rats to electromagnetic field with physical parameters generated by such mobile phone causes in frontal brain cortex an increase in intensity of the process of membrane lipids peroxidation without stimulation of oxidative stress, with accompanying compensatory decrease in the activity of most of analyzed antioxidant enzymes except of catalase, probably due to excessive consumption.
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手机电磁场对大鼠额叶大脑皮层促氧化/抗氧化平衡的影响
本文通过分析手机产生的电磁场$(\mathbf{f}=\mathbf{900\ MHz})$对雄性大鼠额叶大脑皮层促氧化/抗氧化平衡的潜在有害影响,分析了氧化应激标志物和膜脂过氧化标志物的含量,以及选定的抗氧化酶的活性。结果表明,大鼠连续4周(每天4分钟)暴露于此类手机产生的具有物理参数的电磁场中,在不刺激氧化应激的情况下,导致大脑额叶皮层膜脂过氧化过程强度增加,除过氧化氢酶外,所分析的大多数抗氧化酶活性均伴有代偿性降低,这可能是由于过度消耗所致。
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